Precision Macromolecular Chemistry
نویسندگان
چکیده
منابع مشابه
Precision Chemistry for Precision Medicine
During the 2015 State of the Union address, President Obama unveiled plans for a $215 million Precision Medicine Initiative. The details of this plan were laid out by past and present directors of the National Institutes of Health, Harold Varmus and Francis Collins, in a commentary in the New England Journal of Medicine. While the announcement stood as a public statement of support for funding,...
متن کاملComparative precision analysis of Precision-controls on automated chemistry analyzers
Background: Automated diagnostic equipments took over manual testing in last three decades, that allowed enhanced reproducibility, precision and accurateness of results; in addition to 24/7 availability of major lab testing profiles. Aim: In this regard, present study described comparative equipments’ precision assessment of conventional chemistry analyzer, Hirachi 912 with Cobas c501 on parame...
متن کاملAccuracy and precision in clinical chemistry.
Introd u ction Clinical chemistry, for decades restricted to a limited number of chemical tests, has, in recent years, through an increasing awareness of the value of the laboratory investigation of disease, and the introduc tion of automation and sophisticated instru mentation, expanded its field of operations to include a bewildering variety of tests. Advances in biochemical knowledge have ...
متن کاملControlling macromolecular topology with genetically encoded SpyTag-SpyCatcher chemistry.
Control of molecular topology constitutes a fundamental challenge in macromolecular chemistry. Here we describe the synthesis and characterization of artificial elastin-like proteins (ELPs) with unconventional nonlinear topologies including circular, tadpole, star, and H-shaped proteins using genetically encoded SpyTag-SpyCatcher chemistry. SpyTag is a short polypeptide that binds its protein p...
متن کاملQuadruple-precision solution of genome-scale models of Metabolism and macromolecular Expression
Constraint-Based Reconstruction and Analysis (COBRA) is currently the only methodology that permits integrated modeling of Metabolism and macromolecular Expression (ME) at genome-scale. Linear optimization computes steady-state flux solutions to ME models, but flux values are spread over many orders of magnitude. Standard double-precision solvers may return inaccurate solutions or report that n...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Macromolecular Rapid Communications
سال: 2010
ISSN: 1022-1336
DOI: 10.1002/marc.201000728